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Background The role of CD8+ T cells with cytotoxic (CTL) activity of different HIV proteins in controlling HIV-1 infection is still controversial, though a number of studies have suggested that gag-specific CTLs could play a superior role in viral control. The characterization of HIV-1-specific CTLs in genetic diverse individuals infected with locally prevalent HIV-1 strains will provide useful information in elucidating the mechanism of HIV-1 pathogenesis.

P16-12. Relative dominance of Gag-specific cytotoxic T lymphocytes is associated with viral load inversely in HIV-1 clade B' infected Chinese