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Address: 1AIDS Virus Research Unit/Cell Biology, National Institute for Communicable Diseases, Johannesburg, South Africa, 2Columbia University, New York, USA, 3Chris Hani Baragwanath Hospital, Soweto, South Africa, 4National Health Laboratory Services, Johannesburg, South Africa, 5Coronation Women and Children Hospital, Johannesburg, South Africa and 6National Institute for Communicable Diseases and Wits University, Johannesburg, South Africa * Corresponding author

P08-04. The role of class I HLA-B and HLA-Cw in disease progression and maternal-infant HIV-1 transmission in a South African population