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Open Access Oral presentation OA06-06 LB. Evidence of vaccine-induced changes in breakthrough HIV-1 strains from the Step trial M Rolland1, S Tovanabutra2, PB Gilbert3, E Sanders-Buell2, L Heath1, AC deCamp3, CC Magaret3, M Bose2, A Bradfield2, A O'Sullivan2, J Crossler2, W Deng1, H Zhao1, K Wong1, DN Raugi1, J Hural3, S Dubey3, N Frahm3, NL Michael4, J Shiver5, L Corey3, F Li3, SG Self3, J Kim4, S Buchbinder6, DR Casimiro5, MN Robertson5, MJ McElrath3, FE McCutchan4 and JI Mullins*1