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The expression of CD94 and KIRs on HIVand CMV-specific CD8 T cells was investigated with specific tetramer staining, and these NKR were barely detectable at the surface of virus-specific T cells, in contrast to CD85j. Characterization of the maturation stage of CD85jCD8 T cells, and of the impact of CD85j on CD8 T cell response upon TCR triggering with HIV-specific peptides is currently under investigation. from 2005 International Meeting of The Institute of Human Virology Baltimore, USA, 29 August – 2 September 2005

MHC Class I-Specific Inhibitory Receptors on CD8 T Cells – Impact on HIV-specific Activity