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Background HIV-1 subtype-C strains are associated with more than half the infections globally. The molecular nature of the viral subtypes circulating in India is not adequately characterized. In the largest study ever to appear from India, we recently reported a predominance of subtype-C infections in the southern states of the country (Siddappa N.B et al AIDS in press). Unexpectedly, we identified 3 unique B/C recombinant viruses in our cohort that contained envelope of subtype-B origin.

Identification and Biological Characterization of Unique B/C Recombinant Strains of HIV-1 In Southern States of India