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Background To my knowledge, there is only one report on gross deletions in the pol gene (gΔpol) [1] although there are many reports on gross deletions in the nef gene (gΔnef). It is known that Korean red ginseng (KRG) slows depletion of CD4 T cells in human immunodeficiency virus type 1-infected patients [2]. We reported an association between KRG intake and gΔnef [3] in 10 HIV-1 infected patients treated with KRG. Here, we investigated whether KRG intake also induces gΔpol.

Frequent gross deletions in pol gene in 10 HIV-1 infected patients treated with Korean red ginseng for 3 years: dosage dependency