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Background  The present paper describes a topological model of biofeedback. This model incorporates input from a sensory organ and a transduction phase mediated through catecholamine production in the feedback path. The transduction phase comprises both conservative and dissipative systems, from which the appropriate output is combined in a closed loop.    Results  The model has been simulated in MATLAB 6.0 R12 in order to facilitate a comprehensive understanding of the complex biofeedback phenomena concomitant with the transduction phases associated with migraine and with psychosomatic diseases involving digestive disorders.    Conclusion  The complexity of the biological system influences the transduction phase and nature of the system response, which is consequent on the activation of smooth muscles by sympathetic and parasympathetic stimulation.

A topological model of biofeedback based on catecholamine interactions.