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Methods We performed a cross sectional analytic observational study. One hundred twenty three obese children, ages 10 – 14 years with and without acanthosis nigricans got examined for insulin resistance using Homeostasis Model Assessment of Insulin Resistance Index (HOMA-IR). Diagnosis of acanthosis nigricans is confirmed by a dermatologist. This study took place in Wenang district, Manado, North Sulawesi from October 2009 until January 2010.

Correlation between acanthosis nigricans and insulin resistance in obese children in Manado