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Methods In 2 tertiary pediatric centers, Korean girls with early pubertal development were included during 2010-2011. Height, BMI, pubertal stage, chronological age and bone agewere evaluated. LH, FSH, estradiol, IGF-I and IGFBP-3 were measured and a standard GnRH stimulation test was performed.The patients with peripheral precocious puberty were excluded. The peak LH level of ≥5 IU/L was considered pubertal response during GnRH tests.

Basal luteinizing hormone and follicular stimulating hormone: is it sufficient for diagnosis of precocious puberty in Korean girls?