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Background BCAAs (leucine, isoleucine, and valine), particularly leucine, activate key enzymes in protein synthesis after physical exercise. Research has demonstrated that BCAAs increase mTOR phosphorylation and activate p70 S6 kinase in human muscle via an Akt-independent pathway. The extent to which BCAAs influence the anabolic hormone response in conjunction with resistance exercise is not well established. A randomized, double-blind, placebo-controlled study was performed to evaluate the effects of BCAA ingestion in conjunction with an acute bout of lower-body resistance exercise (RE) on various anabolic hormones.

The anabolic hormone response to a lower-body resistance exercise bout in conjunction with oral BCAA supplementation