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Results The clinical picture showed fever in 76.66% of patients, the frequency of joint locations (90%), skin (86.66%), kidney (66.6%) , hematologic (50%) lung (36.66%), gastrointestinal (30%), neuropsychiatric (26.66%) and cardiac (23.3%) involvement. The hematological involvement was detected in 76.66% of our patients, an inflammatory syndrome in 83.33%, immunological disturbances with positive titers of anti- DNAN AC (90%) , ANA (93.6%), and a reduction of the complement (83.33%) . False syphilis serology completed by anti b2Glycoprotein1 antibodies (26%) and anti- cardiolopine were positive in respectively 40, 26 and 20% of cases. Renal involvement is manifested by renal insufficiency in 43% of cases, a significant proteinuria in 50% of cases and prevalence of class IV on biopsy. A case of kikushi fujimoto has been reported as 5 hemophagocytic syndromes. All patients were treated with systemic corticosteroids and hydroxychloroquine. The use of methylprednisolone bolus was indicated in cases of SAM or severe renal impairment associated with cyclophosphamide / MMF and anti-proteinuric medication. Conclusion The prognosis of pediatric SLE remains unpredictable; however it is attached to the renal, neurological and the occurrence of MAS. We mourn two deaths one by neurological attack and other by renal failure.

The systemic lupus erythematous in paediatrics: Moroccan experience of a unit of pediatric rheumatology