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Juvenile idiopathic arthritis (JIA) is the most common cause of chronic anterior uveitis in childhood, and uveitis is the most frequent extra-articular manifestation seen overall in children with JIA. Although it is well-known that ocular involvement is strongly associated with a constellation of particular clinical features, which include the presence of antinuclear antibodies (ANA), young age at disease onset, female sex, and an asymmetric pattern of arthritis, the relative importance of each risk factor is still a matter of debate.

pediatric rheumatology online journal

PReS-FINAL-2028: ANA positivity and a younger age at onset, but not disease category, predict the risk of uveitis in italian children with juvenile idiopathic arthritis