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Lipid profile has been studied in Systemic Lupus Erythematous (SLE) due to the significant morbidity and mortality associated with premature coronary heart disease. Variations in lipid profile in adults with SLE are associated with overall disease activity, with Triglyceride (TG) levels associated with renal flare. Examination of lipid profile in juvenile-onset SLE (JSLE) showed a statistically significant drop in TG in transition from a state of active disease to inactive disease & TG levels to be significantly correlated with proteinuria at diagnosis.

PReS-FINAL-2290: Is an abnormal lipid profile at diagnosis related to increased disease activity in JSLE patients