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Purpose MRI evaluation can be a helpful adjunct to clinical assessment of disease states in adult RA but has not been extensively investigated in children with JIA. MRI is a sensitive examination available to detect active synovial inflammation and can identify bone edema, known to be an important predictor for future joint erosions. By evaluating for such abnormalities, MRI could help differentiate children with active JIA from those with inactive disease (ID). The objectives were to determine if MRI with IV gadolinium (gad) (i) correlates with the clinical state of disease activity and (ii) can biologically confirm the state of clinically ID in children with JIA treated with early aggressive therapy.

MRI findings from the trial of early aggressive therapy (TREAT) study