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Purpose Recent studies have implicated low vitamin D levels with greater disease activity in pediatric systemic lupus erythematosus (SLE) and we have reported an association between low vitamin D levels and greater disease activity in juvenile dermatomyositis. The objective of this study was to explore whether standardized vitamin D supplementation of low levels of 25-hydroxyvitamin D [25(OH)D] might be associated with improvements in disease activity.

Change in disease activity after vitamin D supplementation in children with systemic lupus erythematosus and juvenile dermatomyositis