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Background Myocardial oedema (area-at-risk, AAR) is typically imaged using a pre-contrast T2-weighted short tau inversion recovery (T2w-STIR) sequence on cardiovascular magnetic resonance (CMR) imaging. However, this sequence is prone to motion and rhythm artefact, signal dropout, blood-pool artefact, surface coil signal inhomogeneity and potentially prohibitive long breath-hold duration. This susceptibility to artefacts limits utility of T2w-STIR in large clinical trials where attainment of diagnostic quality oedema imaging in the majority is necessary to determine myocardial salvage: a measure of reperfusion success and a strong predictor of adverse remodeling and prognosis post ST-segment elevation myocardial infarction (STEMI). We compare AAR quantified on T2w-STIR imaging with novel T1-mapping on 3.0T CMR post STEMI.

Comparison of T1-mapping and T2-weighted imaging for diagnostic oedema assessment in ST-segment elevation myocardial infarction