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Background Late gadolinium enhancement (LGE) with CMR is commonly assumed to represent myocardial fibrosis; however, comparative human histological data are limited, and there is no consensus on the most accurate method for LGE quantitation. We evaluated the relationship between CMR assessment of regional fibrosis and infarct size assessment using serial biomarkers after ST segment elevation myocardial infarction (STEMI).

Biomarker validation of cardiac magnetic resonance analysis of regional myocardial fibrosis in ischaemic heart disease