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Background The accurate assessment of arterial blood flow is crucial for the diagnosis and management of patients with cardiovascular disease. Our aim was to systematically compare three phase-contrast (PC) MRI sequences for the quantification of aortic hemodynamics, including: 1) 2D time-resolved (CINE) PC MRI with one-directional through-plane (2D-1dir) velocity encoding; 2) 2D CINE PC MRI with three-directional (2D-3dir) velocity encoding; 3) 4D flow MRI with full volumetric coverage of the aorta and three-directional velocity encoding.

4D Flow and 2D PC MRI: impact of volumetric coverage and three-directional velocity encoding on quantification of aortic hemodynamics