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Background Bicuspid aortic valve (BAV) is known to be heritable and often shows a concomitant aortopathy which was thought also to be present in some family members. While one recent study reported normal ascending aortic diameters in family members of the general BAV population, little is known about aortic function in such family members. We used advanced aortic cardiovascular magnetic resonance (CMR) and peripheral blood analysis to assess evidence for an underlying aortopathy in family members of bicuspid aortic valve patients.

Inherited aortopathy assessment in bicuspid aortic valve disease relative