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Background Cardiac involvement in systemic light-chain (AL) amyloidosis is caused by the extracellular deposition of misfolded AL immunoglobulin and carries a poor prognosis. Cardiac magnetic resonance (CMR) T1 mapping and extracellular volume (ECV) measurements may have advantages over late gadolinium enhancement (LGE) for early diagnosis and quantifying of amyloid burden. The aim of this study was to explore the diagnostic value of ECV for cardiac amyloidosis and compared ECV values calculated by postcontrast T1 mapping got in different delay time.

journal of cardiovascular magnetic resonance

3.0T Cardiac Magnetic Resonance Quantification of Myocardial Extracellular Volume using different delay time of post-contrast T1 mapping for the Diagnosis of Cardiac Amyloidosis