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Results 66% of the patients were male, mean age 52 ± 18 years, mean wall thickness was 19 ± 4 mm. Amongst the 9 patients with LVNC, 5 had VT/VF, 2 had SVT and 2 had syncope. Patients with LVNC had a significantly higher prevalence of ventricular arrhythmia than those without LVNC (56% vs 18%, p = 0.03), with a relative risk of 3.0 (95% CI 1.3 6.9). LV septal thickness (18.4 ± 5.6 mm vs 18.7 ± 3.5 mm, p = 0.9) and ejection fraction (70 ± 7.7 vs 70 ± 10.5%, p = 0.9) did not significantly differ between those with LVNC and those without. Presence of LV scar assessed by late gadolinium enhancement was similar between the groups (89% vs 73%, p = 0.7). Conclusions Presence of LVNC may be associated with ventricular tachyarrhythmia in HCM patients and may provide a new phenotypic marker for adverse prognosis, especially in the intermediate risk group. Further studies in larger populations are required to assess its possible prognostic value.

Presence Of Left Ventricular Non Compaction In Hypertrophic Cardiomyopathy Is Associated With Arrhythmia