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Background Mid-wall striae pattern late gadolinium enhancement (LGE) has been shown to independently predict future outcomes in patients with dilated non-ischemic cardiomyopathy (NICM). Standardized quantification tools are of particular interest for clinical translation of this novel imaging marker. However, signal intensity (SI) based threshold techniques, such as Signal Threshold versus Reference Mean (STRM) and Full Width at Half Maximum (FWHM), have been inconsistently applied and their performance in this population is unknown. The purpose of this study was to compare the accuracy of semi-automated LGE quantification techniques against expert-prescribed threshold assignment in patients with NICM.

journal of cardiovascular magnetic resonance

Comparison of Semi-automated Late Gadolinium Enhancement Quantification Techniques in Measuring Septal Fibrosis in Patients with Dilated Non-Ischemic Cardiomyopathy