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Background An international Consensus Group established the proposed cardiovascular MR (CMR) criteria for diagnosis of acute myocarditis (Lake Louise Criteria) in 2009, consisting of 3 tissue markers: irreversible tissue injury on late gadolinium enhanced (LGE) images, edema on T2 STIR images and hyperemia on early enhanced (EE) images. The purpose of this study was to test the variability between the different CMR centers for the diagnosis of myocarditis based on Lake Louise Criteria.

Inter-center variability in the application of the Lake Louise Criteria to the diagnosis of myocarditis