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Background The presence of myocardial fibrosis is associated with worse clinical outcome in hypertrophic cardiomyopathy (HCM) patients. Due to the substantial variations in left ventricular (LV) wall thickness and fibrosis in HCM, volumetric coverage of entire LV myocardium is essential for the accurate assessment of myocardial fibrosis. Slice-interleaved T1 (STONE) mapping sequence allows for the assessment of native T1 time with complete coverage of LV myocardium. The aim of this study was to investigate whether STONE sequence is useful for the assessment of regional variability of LV native T1 time in HCM patients.

journal of cardiovascular magnetic resonance

Diffuse Myocardial Fibrosis detected by Multi-slice T1 Mapping using Slice Interleaved T1 (STONE) Sequence in Patients with Hypertrophic Cardiomyopathy