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Background The European Society of Cardiology recognizes different hypertensive heart disease (HHD) phenotypes. HHD can be classified into 4 left ventricular (LV) phenotypes by indexed LV mass, mass to volume ratio (M:V) and indexed end diastolic volume (EDV) (Table 1). All remodeling/ hypertrophy phenotypes carry adverse cardiovascular prognosis, but the underlying mechanisms are incompletely understood. We investigated differences in intra/extracellular myocardial structure and function between phenotypes with T1 mapping and myocardial strain analysis.

Comprehensive intra/extracellular myocardial structural and functional characterization of hypertensive heart disease phenotypes