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Background LA strain, measured by feature-tracking using cine MRI, is an emerging tool for regional evaluation of the left atrium [1-4]. Late gadolinium enhancement (LGE MRI) is a method which indicates regions of possible atrial fibrosis. Their regional relationship is not known. Our goal was to compare global and regional left atrial (LA) strain in atrial fibrillation (AF) subjects and controls, and relate strain globally to LA volumes and ejection fraction (EF), and regionally to the presence of fibrosis. Does LA strain reflect fibrosis?

Lower left atrial strain in the presence of regional atrial fibrosis: an MRI study of patients with atrial fibrillation