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Background In 2004 seven Italian centers reported survival data for patients with thalassemia major (TM) and showed that heart disease due to iron overload was the most common cause of death (Borgna et al Haematologica 2004). In the same years the accurate and noninvasive assessment of cardiac siderosis was made possible in Italy by the introduction of the T2* cardiovascular magnetic resonance (CMR). We aimed to evaluate if the deployment of T2* CMR had an impact on the mortality rate.

Significant improvement of survival by T2* CMR in thalassemia major