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Background Considering that nonresponse rates to cardiac resynchronization therapy (CRT) are typically 35-50%, assessment of the cardiac substrate for CRT with cardiac imaging could be very helpful for many patients with heart failure referred for this therapy. We have previously shown that CMR assessment of dyssynchrony using displacement encoding with stimulated echoes (DENSE) is strongly associated with CRT response; however, there has not yet been a direct comparison between this CMR methodology and more commonly used 2D speckle tracking echocardiography (STE) dyssynchrony parameters.

Comparison of CMR DENSE strain imaging and 2D speckle tracking echocardiography for cardiac resynchronization therapy (CRT) response