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Background SASHA and MOLLI T1 mapping sequences can have errors in calculated T1 values when their magnetization preparation pulses do not fully saturate/invert magnetization [1,2]. The commonly used 90°-90°-90° saturation pulse train [3] has poor performance at 3T due to large B1 field inhomogeneities. We propose that a new hard RF pulse train with numerically optimized flip angles [4] will offer superior performance and reduce errors in SASHA T1 values due to incomplete saturation.

Optimized saturation pulse rrains for SASHA T1 mapping at 3T