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Background A single-bolus non-ECG-triggered method was previously proposed to reduce the complexity of quantitative myocardial perfusion imaging [1]. Compared to conventional dual-bolus method, the arterial input function (AIF) is derived from imaging data, eliminating the need for an additional scan. The imaging workflow is further simplified by retrospectively determining the proper reconstruction window, eliminating the dependency on ECG triggering. However, only a single slice was acquired. In this work, we expand upon the previous technique to 3 slices using highly constrained back projection (HYPR) reconstruction to achieve clinically acceptable myocardial coverage.

Three slice myocardial coverage using non-ECG-triggered perfusion imaging with integrated T1 mapping for quantifying myocardial blood flow