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Background MR stress perfusion is a non-invasive, reliable and safe test for ischemic heart disease [1]. Recent publications reported sensitivity and specificity of 89% and 80% respectively [2]. Image quality improvements seem to be essential for improving the predictive value of the method. This leads to the dilemma of finding a compromise between high spatial resolution and sufficient SNR. Lately iterative reconstruction demonstrated great promise in improving SNR [3]. The aim of the current study was to compare cardiac perfusion in 24 patients reconstructed with product and a novel prototype iterative reconstruction. Methods 24 patients (mean age 62 ±15) were examined on a 1.5T clinical MR scanner (MAGNETOM Aera, Siemens AG, Erlangen, Germany) using a saturation prepared TFL product sequence with the following parameters: TR/TE=331/1.4ms ; Flip angle = 12°; BW = 668Hz/Px; Voxel size=0.8×0.8×10.0 mm (inplane interpolated); FOV=290mm2; Matrix = 170x192; Slice thickness=10mm; Acceleration=2; Inversion time= 180ms; Phase oversampling=60%; Motion correction. Pharmacological stress was applied using Adenosine (Adenoscan, Sanofi-Synthelabo). Gadolinium-based contrast agent (Magnevist, Bayer Schering Pharma) was

Initial experience for first pass cardiac perfusion with iterative reconstruction in patients