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Background Recent research has shown that the size of myocardial gray zone (a mixture of normal and infarcted tissue) identified from late gadolinium enhanced (LGE) MRI is an independent predictor of adverse cardiac events in post-infarction patients. However, definition of myocardial gray zone in LGE images (e.g. using the N-STD method) remains difficult for varying MR protocols and qualities, lacks histological validation, and may lead to conflicting conclusions. We sought to establish a novel predictive scar parameter independent of gray zone definition.

Myocardial scar surface area identified by LGE MRI is an independent predictor of mortality in post-infarction patients