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Background Extracellular volume fraction (ECV) calculation requires myocardial and blood T1 measurements to be acquired preand post-contrast administration. T1 star (T1*) may offer a more accurate estimation of blood pool T1 as it avoids look-locker correction, and so is theoretically a more robust measure of blood T1 where fresh spins are flowing into the image plane. Reproducibility of blood T1 and T1* has not been as extensively explored as myocardial T1. We compared the precision and reproducibility of blood T1* using a Modified LookLocker Inversion recovery sequence (MOLLI), against standard T1 measurements.

Precision and reproducibility of blood T1 estimation: implications of T1 star on ECV calculation