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Background Significant morphological heterogeneity is known to exist among subjects with bicuspid aortic valves (BAV). Accompanying this is the recognition of varied penetrance of phenotypic aortopathy. A genetic contribution possibly influenced by blood flow patterns in the aortic root has been postulated. Current BAV classification schemes do not comprehensively characterize the heterogeneous expression of BAV morphology (Fig 1a). The purpose of this study is to describe a novel comprehensive classification system for BAV morphology in a consecutive cohort of patients referred for evaluation of the thoracic aortic size.

A novel comprehensive classification system for bicuspid aortic valve morphology at cardiac MRI and initial results in 368 patients