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Background Impaired microvascular reperfusion (no-reflow) and unsuccessful infarct-related artery (IRA) revascularization are associated with a worse clinical outcome in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). Reperfusion can be identified by epicardial or microvascular flow determined by angiography as Thrombolysis in Myocardial Infarction (TIMI) flow grade and a myocardial blush grade (MBG), respectively. Moreover, microvascular obstruction (MVO) determined by CMR is also a well-known predictor of an unfavorable clinical outcome after STEMI. The aim of the study was to determine the effect of impaired reperfusion estimated by angiography on microvascular obstruction and infarct size (IS) measured by CMR.

Extent of infarct size and microvascular obstruction following unsuccessful reperfusion in patients with ST-segment elevation myocardial infarction