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Background Cardiac magnetic resonance elastography (CMRE) is a novel imaging technique to noninvasively quantify myocardial stiffness. Previous studies have demonstrated that excess interstitial fluid or fibrosis causes increased myocardial stiffness and also alter T1, T2 relaxation times, and myocardial extracellular volume fraction (ECV). Nonetheless, T1, T2 and ECV have not yet been correlated with either invasive or noninvasive measures of myocardial stiffness. The aim of our study was to demonstrate the feasibility of quantifying right ventricular free wall (RVFW) stiffness using CMRE and correlate it with intrinsic myocardial relaxation times and ECV in dogs with severe congenital pulmonary valve stenosis causing RV hypertrophy.

journal of cardiovascular magnetic resonance

MR elastography-derived right ventricular myocardial stiffness in dogs with congenital pulmonary valve stenosis: correlation with myocardial relaxation times and ECV