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Background Peripheral arterial disease (PAD) is accompanied by a complex lower limb pathophysiology resulting in reduced functional capacity and quality of life. We aim to characterize the exercise recovery kinetics in the calf muscle of healthy volunteers by combining treadmill exercise and magnetic resonance (MR) relaxometry (T1, T2 and T2*), and to investigate their relation with age and treadmill exercise duration.

Integrated treadmill stress testing and MR relaxometry (T1, T2, T2*): response in healthy calf muscles