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Methods 9 healthy volunteers and 7 patients with no evidence/ history of disease were scanned on a Siemens Avanto 1.5T scanner and a 32 channel coil using the Siemens modified look locker inversion recovery (MOLLI) WIP version 448B (5:3:3 acquisition with inline motion correction and T1 map generation). All subjects had a 4 chamber, basal and mid ventricular short axis acquisition performed. In all slices, a single, slender ROI was placed in the mid wall of the left ventricular septum with meticulous attention to avoiding partial volume of blood pool. In addition, the mid ventricular short axis slice was segmented (with aggressive endo and epicardial border pruning) into 6 AHA segments to allow regional T1 analysis.

The effect of gender, piloting and segmental analysis on T1 quantification in normal individuals using MOLLI