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Background Previous studies have demonstrated that an increase in extracellular volume measured on MRI is directly proportionate to myocardial fibrosis. Myocardial extracellular volume is proportionate to partition coefficient (l) and extracellular volume = l × (1-hematocrit). l can be measured by assessing the T1 relaxation time before and after injection of contrast medium. The goal of this study is to assess the accuracy and precision of several T1 mapping sequences using a phantom at 1.5 and 3.0T.

Accuracy and precision of myocardial T1mapping with MOLLI and ShMOLLI at 1.5T and 3.0T: a phantom study