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Background While late gadolinium enhanced (LGE) MRI is the gold standard for detection of focal myocardial scarring [1], it is less effective than cardiac T1 mapping (ECV) for detection of diffuse fibrosis. LGE, in principle, can be synthesized from cardiac T1 maps. We sought to derive synthetic LGE images from saturation-recovery based cardiac T1 maps for simultaneous assessment of focal and diffuse cardiac fibrosis.

Synthetic LGE derived from cardiac T1 mapping for simultaneous assessment of focal and diffuse cardiac fibrosis