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Background Actual methods to quantify wall shear stress (WSS) are performed on reformatted 2D planes from 4D flow data sets. This approach has the inherit limitation that only a few planes are analyzed on specific locations of the aorta, even though the full 3D velocity field is usually available. Another problem with this approach is that the process of locating 2D planes manually is dependent on the user and may lead to results that have low reproducibility. These problems can be circumvented by calculating the WSS in 3D directly. A few methods based on computational fluid dynamics (CFD) have been proposed to obtain 3D WSS. These methods use realistic vascular geometries extracted from MR data, however, assumptions are made on the properties of the walls and on flow velocity profiles that may not be fully realistic. In this work, we propose a novel methodology based on finite-element (FE) interpolations to compute the 3D WSS of the whole thoracic aorta from 4D flow MRI data.

3D quantification of wall shear stress using finite-element interpolations from 4D flow MR data in the Thoracic Aorta