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Conclusions Patients with MR demonstrate a spectrum of myocardial fibrosis associated with reduced longitudinal and circumferential deformation and reduced peak VO2 max. These changes occur before changes in conventional markers of LV structure and function or an increase in BNP. The routine use of CMR may provide a rationale for improved risk stratification in patients with asympto

Optimum management of asymptomatic moderate-severe degenerative mitral regurgitation: a role for T1 mapping in risk stratification?