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Background Late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) is considered the gold standard for quantification of myocardial infarction in vivo. Myocardium with increased fractional distribution volume (fDV) due to acute necrosis or chronic scar exhibit hyperenhancement relative to viable myocardium when using a gadoliniumbased extracellular contrast agent. Previous studies have

Infarct size is overestimated by contrast-enhanced CMR in the acute phase but not at 7 days when compared with histopathology