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Background Systemic sclerosis (SSc) is characterized by widespread tissue fibrosis including the myocardium. Diffuse myocardial fibrosis can be detected non-invasively by extracellular volume (ECV) imaging based on preand postcontrast T1 measurements using cardiovascular magnetic resonance (CMR). We hypothesized that multiparametric CMR, including T1 mapping, can detect subclinical myocardial involvement and provide a comprehensive cardiac assessment in patients with SSc.

journal of cardiovascular magnetic resonance

Systemic sclerosis: detection of early subclinical diffuse myocardial fibrosis and impaired left ventricular strain by cardiovascular magnetic resonance