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Background Fractional flow reserve (FFR) is an invasive procedure evaluating the functional significance of an intermediate stenosis by measurement of pressure drop across stenosis [1]. Noninvasive pressure measurement technique i.e. Phase-contrast (PC)-MRI has been studied in the cardiac chamber[2], aorta[3], and renal[4] arteries. The purpose of this study was to investigate the feasibility of pressure gradient quantification using 4DPC-MRI in the coronary arteries, which may allow for the derivation of FFR associated with stenosis.

Pressure gradient measurement in the coronary artery using 4D PC-MRI: towards noninvasive quantification of fractional flow reserve