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Background It has been shown that both the degree of LV mechanical dyssynchrony and the location of the latest contracting segment of the LV affect an individual’s ability to respond positively to CRT [Bax et al JACC 2005]. From high temporal resolution short-axis SSFP images, maps of regional mechanical contraction times throughout the LV can be generated. These maps show regional dyssynchrony and can be used to assist in CRT lead placement planning. The objective of this study was to: 1) characterize the mechanical contraction times typically observed in a healthy population and determine threshold values for normal contraction times and 2) apply these thresholds in a set of patients enrolled for CRT to determine the size and location of areas of late mechanical contraction (dyssynchronous regions).

Identification of the size and location of dyssynchronous regions in patients undergoing CRT