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Background Myocardial T1 mapping remains a challenging task due to restrictions imposed by cardiac and respiratory motion. Modified Look-Locker Inversion Recovery (MOLLI) [1] is widely used for 2D cardiac T1-mapping. In MOLLI, the spin-lattice relaxation curve is sampled several times after a single magnetization preparation. The ECG triggered imaging induces a disturbance in the relaxation curve, which varies based on the heart rate. Hence, MOLLI T1 measurements show strong correlations to the heart rate especially in pre-contrast. We developed a novel T1 mapping sequence that enables heart-rate invariant myocardial T1 mapping.

Heart-rate independent myocardial T1-mapping using combined saturation and inversion preparation pulses