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Background Arterial wall stiffening and thickening are part of the atherosclerosis process leading to luminal narrowing. A close link between distal aortic pulse wave velocity (PWV) and peripheral vascular disease, reflecting sitespecific relationship between local plaque burden and vascular disease, is hypothesized. Purpose of this study was to compare peripheral arterial stenosis severity on contrast-enhanced MR angiography (CE-MRA) with regional aortic wall stiffness, expressed by PWV and acquired with velocity-encoded (VE) MRI, and vessel wall (VW) thickness sampled in the left common carotid artery with 3T Black-Blood (BB) MRI.

journal of cardiovascular magnetic resonance

Site-specific coupling between aortic pulse wave velocity, carotid vessel wall thickness and peripheral stenosis severity in peripheral arterial occlusive disease at 3T MRI