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Background Accurate characterization of myocardial scar has important diagnostic and prognostic implications for post-infarct patients. Previous studies have used late gadolinium enhanced (LGE) MR to characterize myocardial scar, by dividing the scar region into core and gray zones based on signal intensity in LGE. The characterization is however subjective to manual annotations, dependent on image acquisition parameters, contrast dose and timing, and has limited reproducibility. The purpose of this study is to objectively and reproducibly characterize infarcted myocardial tissue combining information from the LGE and post-contrast Look-Locker (LL) sequences.

A new method for objective myocardial scar characterization using MR late gadolinium enhancement and post-contrast look-locker sequences