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Background Systematic review of 1142 patients with acute heart failure presenting to St George’s Hospital in South London has revealed a high prevalence of transthyretin (TTR) amyloidosis in patients of African descent. This is in keeping with the reported gene frequency of variant TTR V122I in 4% of African Americans. Availability of on-site cardiac MRI (CMR) has facilitated this high detection rate.

High yield of cardiac MRI in the investigation of elderly heart failure patients of African descent